General Information
Job Advert Title: Scientist, Gene Regulation Technology
Location: Tsukuba
Division: Cell and Gene Therapy Research
Employment Class: Permanent
Description
【募集の背景 / Purpose & Scope】The position contributes to create candidates of gene therapy products by vector design, vector construction and in vitro evaluation including high throughput and data scientific approach.【職務の内容 / Essential Job Responsibilities】（雇入れ直後）•Contribute to the payload design and selection for multiple gene therapy projects (such as AAV, but not limited to AAV).•Conduct screening of parts (such as promoters), sequence design, small-scale production, and evaluation in collaboration with members of project team and other departments.•Contribute to the patent strategy such as FTO analysis and patent filing in collaboration with IP, and data-science driven payload design activities in collaboration with CMC and DX.•Keep up with scientific knowledge on novel technologies on gene therapy product design.•Support the evaluation of external opportunities. •Report to senior scientist, team lead or head of Gene Regulation Technology in GT Engineering, and well aligned with steak holders.
（変更の範囲）会社内での全ての業務
【就業環境に関する要件 / Specific Physical or Environmental Requirements】•This position is based in Tsukuba in Japan and will require on-site work to manage wet lab works.
【応募要件 / Qualifications】＜必須 / Required＞•PhD in molecular biology or related sciences. •3+ years of experience in drug discovery research. •Experience in the field of gene therapy.•Knowledge and experience in GT modality design and small-scale production such as AAV vector.•Technical proficiency in cell and molecular biology techniques, vector sequence design, plasmid vector construction, virus production and cell-based assay.•Experience working as a research project team member within a multinational cross-functional team.•Excellent written and verbal communication and presentation skills.
＜歓迎 / Preferred＞•Be familiar with multiple areas of biology and technologies.•Be familiar with machine learning/AI-based approaches to gene therapy.•Be familiar with ophthalmology, central nerve system or neuromuscular diseases. •Experience with pooled library screening•Experience working in global, cross-functional team consisting of different backgrounds.•Experience in patent filing and FTO analysis.•Experience in collaboration research with academia/biotech or evaluation of external opportunities.
【応募書類 / Application Documents】和文履歴書（必須）・和文職務経歴書（必須）・英文レジュメ（任意）Resumes
【選考プロセス / Selection details】書類選考 → 1次面接 → 適性検査 → 最終面接※変更の可能性もございますので、予めご了承下さい。CV screening → First interview → Aptitude test → Final interview*Please be advised that there might be a change in the process.
【勤務地 / Location】（雇入れ直後）茨城県つくば市 アステラス製薬 つくば研究センターTsukuba, Ibaraki※ＪＲひたち野うしく駅とつくばエクスプレス（TX) 研究学園駅より通勤バスがございます。
（変更の範囲）会社の定める事業場および自宅
【勤務開始日 / Start Date】応相談Will be decided according to the candidate's flexibility
【契約期間 / Contract Duration】期間の定めなしNot limited to specified period
【試用期間 / Probation Period】試用期間原則なしNo probation period in principle
【給与 / Salary】①基本給：当人の経歴・技術・技能等を考慮して決定②裁量労働制の場合：裁量労働手当として職務グレードに応じて50,000～100,000円支給③フレックスタイム制の場合：月間の所定労働時間を超えて勤務する時間に対して時間外勤務手当を支給①Base salary: will be decided by the candidate's experience, skill and capability.②When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000～100,000yen, based on the Grade)③When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.
【昇給 / Salary Raise】有り
【賞与 / Bonus】有り
【諸手当 / Allowance】裁量労働手当、住宅手当、通勤手当 等Discretionary work allowance, Housing allowance, Commutation allowance, etc.
【勤務時間 / Working Hours】8:30～17:30（月～木）、8:30～15:45（金）、専門業務型 裁量労働制裁量労働制の場合、所定労働時間を働いたものとみなす。 8:30～17:30（Mon～Thu）、8:30～15:45（Fri）Discretionary Work System
【休日 / Holidays】完全週休２日制（土曜・日曜）、祝日、5月1日、夏季、年末年始Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays
【休暇 / Vacation Leave】年次有給休暇、育児休業制度、介護休業制度 等Annual paid leave, childcare leave system, nursing care leave system, etc.
【福利厚生 / Welfare】雇用保険、労災保険、厚生年金、健康保険、共済会制度、社宅制度、持株会制度、財形貯蓄制度 等Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System
【アステラス製薬 採用サイト/ Career web site】https://re-jp.astellas.com/jp/recruit/newgraduates/For more information about Astellas, please visit our career web site."We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."
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